LACTOSE-NEGATIVE STRAINS Lactobacillus helveticus CAPABLE TO PRODUCE HYPOTENSIVE TRIPEPTIDE IPP AND VPP AND METHOD OF PRODUCING THEREOF, APPLYING STRAINS FOR PRODUCING FERMENTED MILK PRODUCT, FERMENTED MILK PRODUCT AND METHOD OF PRODUCING THEREOF Russian patent published in 2011 - IPC C12N1/20 C12N15/01 A23C9/123 A61K35/74 

FIELD: medicine.

SUBSTANCE: lactose-negative strains Lactobacillus helveticus CNCM 1-3504, Lactobacillus helveticus CNCM 1-3505 and Lactobacillus helveticus CNCM 1-3508 do not have the ability to transform lactose in lactic acid and are able to producing hypotensive tripeptides IPP and VPP; they are used in a method of producing a fermented milk product exhibiting antihypertensive properties. The strains are prepared by contact of at least one strain and an effective amount of Streptozocin with lactose added.

EFFECT: stable shelf-life peptide content in the product and high strain population.

14 cl, 6 dwg, 3 tbl, 4 ex