FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to a compound which represents 6-(3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)-N-methylnicotine amide 
, or to its pharmaceutically acceptable salt. This compound and its pharmaceutically acceptable salts exhibits affinity to a histamine H3 receptor and are antagonists and/or inverse agonists of said receptor.
EFFECT: development of an effective method of producing the benzazepin derivative, the pharmaceutical compositions containing it, and application of the benzazepin derivative for treating neurological and psychiatric disturbances.
18 cl, 6 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| (3-CYCLOALKYL-2, 3, 4, 5 - TETRAHYDRO-1H-BENZO [d] AZEPIN-7-YLOXY) DERIVATIVES, USE THEREOF FOR INHIBITING H3 RECEPTORS, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD | 2003 |
|
RU2388752C2 |
| CONDENSED AZEPINE DERIVATIVES AS ANTIDIUTETIC AGENTS | 2001 |
|
RU2269517C2 |
| BENZAZEPIN DERIVATIVES APPLICABLE AS VASOPRESSIN ANTAGONISTS | 2008 |
|
RU2471784C2 |
| DERIVATIVES OF 1,2,4,5-TETRAHYDROBENZO[D]AZEPINES AND MEDICINAL AGENT BASED ON THEREOF | 2000 |
|
RU2240317C2 |
| CONDENSED AZEPINES, PHARMACEUTICAL COMPOSITION COMPRISING THEREOF, METHOD FOR TREATMENT BY USING INDICATED COMPOSITION | 2001 |
|
RU2259367C2 |
| COMPOUNDS | 2003 |
|
RU2327690C2 |
| BICYCLIC AGONISTS OF VASOPRESSIN | 2000 |
|
RU2254332C2 |
| PHARMACEUTICAL COMPOSITIONS INCLUDING NEP (NEUTRAL ENDOPEPTIDASE) INHIBITORS, INHIBITORS OF ENDOGENOUS ENDOTHELIN-PRODUCING SYSTEM AND HMG (HYDROXYMETHYLGLUTARYL) CoA REDUCTASE INHIBITORS | 2005 |
|
RU2410118C2 |
| THIOPHENYL AND PYRROLYL AZEPINES AS SEROTONIN 5HT RECEPTOR LIGANDS AND USE THEREOF | 2007 |
|
RU2434872C2 |
| MODULATORS OF 5-HT RECEPTORS | 2003 |
|
RU2317982C2 |
