DERIVATIVES OF 1,2,4,5-TETRAHYDROBENZO[D]AZEPINES AND MEDICINAL AGENT BASED ON THEREOF Russian patent published in 2004 - IPC

Abstract RU 2240317 C2

FIELD: organic chemistry, medicine.

SUBSTANCE: invention describes derivatives of 1,2,4,5-tetrahydrobenzo[d]azepines of the general formula (I):

wherein X means -N=, =N-, -N<, >C= or =C<; Y means -N=, =N-, -NH-, -CH= or =CH-; dotted line can mean a bond; radicals R1-R16 are described in the invention claim, and also their pharmaceutically acceptable salts in their racemic and optically active form. Also, invention describes a medicinal agent that can be used in treatment or prophylaxis of acute and/or chronic neurological disorders. Invention provides preparing new compounds eliciting useful biological properties.

EFFECT: valuable medicinal properties of compounds.

13 cl, 1 tbl, 276 ex

Similar patents RU2240317C2

Title Year Author Number
(3-CYCLOALKYL-2, 3, 4, 5 - TETRAHYDRO-1H-BENZO [d] AZEPIN-7-YLOXY) DERIVATIVES, USE THEREOF FOR INHIBITING H3 RECEPTORS, PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD 2003
  • Bamford Mark Dzhejms
  • Din Dehvid Kennet
  • Sekhmi Sandzhit Singkh
  • Uilson Dehvid Mehtt'Ju
  • Vizerington Dzhejson
RU2388752C2
PYRROLIDINE DERIVATIVES APPLICABLE AS CATEPSIN DERIVATIVES 2011
  • Behnner Dehvid
  • Greter Uve
  • Khaap Vol'Fgang
  • Kjune Khol'Ger
  • Mauzer Kharal'D
  • Plansher Zhan-Mark
RU2548684C2
DERIVATIVES OF SUBSTITUTED DIBENZOAZEPINE AND BENZODIAZEPINE, USEFUL AS INHIBITORS OF γ -SECRETASE 2004
  • Flor Aleksander
  • Gallej Guido
  • Jakob-Retne Roland
  • Kitas Ehrik Argirios
  • Peters Jens-Uve
  • Vostl' Vol'Fgang
RU2356895C2
NOVEL HETEROCYCLIC COMPOUNDS AS BRD4 INHIBITORS 2016
  • Mulakala, Chandrika
  • Sivanandhan, Dhanalakshmi
  • Gondrala, Pavan Kumar
  • Chinnapattu, Murugan
  • Rajagopal, Sridharan
  • Vadivelu, Saravanan
RU2721120C2
DERIVATIVES OF DIHYDROBENZODIAZEPIN-2-ONE FOR TREATMENT OF NEUROLOGICAL DISORDERS 2003
  • Geo Adam
  • Ehrvin Getshi
  • Jurgen Vikhmann
  • Tomas Iogannes Vol'Tering
RU2315764C2
BICYCLIC LACTAMS AND METHODS FOR USE THEREOF 2016
  • Patel Snakhel
  • Gamilton Gregori
  • Stivala Krejg
  • Chen Khuejfen
  • Chzhao Gujlin
RU2716136C2
SUBSTITUTED 4-(ARYLAMINO) SELENOPHENOPYRIMIDINE COMPOUNDS AND METHODS OF THEREOF APPLICATION 2011
  • Gokaradzhu Ganga Radzhu
  • Kasina Sudkhakar
  • Somepalli Venkatesvarlu
  • Gokaradzhu Rama Radzhu
  • Gokaradzhu Venkata Kanaka Ranga Radzhu
  • Bkhupatkhiradzhu Kiran
  • Golakoti Trimurtulu
  • Sengupta Krishanu
  • Alluri Venkata Krishna Radzhu
RU2566293C2
BETA-SECRETASE INHIBITORS 2016
  • Bartels Bern
  • Dolente Kozimo
  • Guba Volfgang
  • Khaap Volfgang
  • Obst Zander Ulrike
  • Peters Jens-Uve
  • Voltering Tomas
RU2712272C2
NEW COMPOUNDS AND DERIVATIVES OF SULFONIMIDEOILPURINON FOR TREATMENT AND PROPHYLAXIS OF VIRAL INFECTION 2016
  • Lyan, Chungen
  • Myao, Kun
  • Van, Tszyanpin
  • Yun, Khunin
  • Chzhen, Syufan
RU2745269C2
NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND COSMETICS 2015
  • Fournier Jean-Francois
  • Clary Laurence
  • Thoreau Etienne
RU2712971C2

RU 2 240 317 C2

Authors

Geo Adam

Al'Fred Binggeli

Khans-Peter Mehrki

Vensan Mjutel'

Moris Vil'Khel'M

Vol'Fgang Vostl'

Dates

2004-11-20Published

2000-08-04Filed