PHENYLOXYANILINE DERIVATIVES LABELLED WITH RADIOACTIVE HALOGEN Russian patent published in 2011 - IPC C07C233/25 C07B59/00 A61K51/00 

Abstract RU 2425824 C2

FIELD: chemistry.

SUBSTANCE: novel phenyloxyaniline derivative labelled with radioactive halogen has formula (I), where R1 denotes an unsubstituted alkyl group having 1-10 carbon atoms, X4 denotes a hydrogen atom, and X1, X2 and X3 are identical or different and each denotes a hydrogen atom, an alkoxy group, having 1-5 carbon atoms, a halogen atom, or a radioactive halogen atom selected from a group comprising 121I, 123I, 124I, 125I, 131I, provided that X2 or X3 denote a radioactive halogen atom selected from a group comprising 121I, 123I, 124I, 125I, 131I, which is a compound which is suitable during early detection, prevention and treating diseases such as dementia of the Alzheimer's type.

EFFECT: more effective use of the compounds.

3 cl, 6 ex, 2 dwg

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RU 2 425 824 C2

Authors

Suzuki Kazutosi

Sukhara Tetsuja

Kristar Khal'Din

Chzhan Min-Zhun

Nakazato Atsuro

Dates

2011-08-10Published

2005-12-28Filed