FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to benzothiazole derivatives of general formula (I) in which R1 represents -OH; R2 represents radioactive fluorine; R3 represents hydrogen, and R4 represents C1-C6 alkyl; and to their pharmaceutically acceptable salts. Also the invention refers to a pharmaceutical composition showing the property to bind amyloid for detecting amyloid deposits, containing an effective amount of a benzothiazole derivative of formula (I) 
and a pharmaceutically acceptable carrier, and to a method of detecting amyloid deposits in a mammal by introduction of the evaluated amount of the benzothiazole derivative of formula (I) able for specific binding with amyloid deposits with following detection of the bound amount.
EFFECT: making the benzothiazole derivative for life-time amyloid deposits imaging in patients.
5 cl, 22 dwg, 2 tbl, 17 ex
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