INDOLE DERIVATIVES SUITABLE FOR VISUALISATION OF NEUROINFLAMMATION Russian patent published in 2014 - IPC C07D495/04 A61K31/382 A61K31/407 

Abstract RU 2512288 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compound of formula I , which represents agent of in vivo visualisation of peripheral benzodiazepine receptor (PBR), where Q represents hydrogen or fluorine; X represents hydrogen or C1-4alkoxy; Y represents S; and R represents C1-6fluoroalkyl; and where, at least, one atom of said agent of in vivo visualisation of formula I represents radioisotope, suitable for in vivo visualisation and representing either gamma-emitting radioactive halogen or positron-emitting radioactive non-metal; and where if said radioisotope is a carbon radioisotope, it is carbonyl carbon.

EFFECT: obtaining novel derivatives.

15 cl, 2 dwg, 1 tbl, 12 ex

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RU 2 512 288 C2

Authors

Uehdsuort Khehrri Dzhon

Shan Bo

O'Shi Dennis

Passmor Dzhoanna Mari

Trigg Uil'Jam Dzhon

Dates

2014-04-10Published

2009-10-02Filed