FIELD: chemistry.
SUBSTANCE: disclosed is a method of producing surface-modified nanoparticles for immobilising biological substances. The method involves modifying Fe3O4 nanoparticles containing ester groups. The obtained particles are then treated with aminopropyl triethoxy silane. Further, the suspension of nanoparticles is incubated with a condensing agent and the enzyme is immobilised.
EFFECT: method enables to obtain immobilised preparations with high enzyme specific activity.
3 tbl, 3 ex
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Authors
Dates
2011-08-10—Published
2010-02-16—Filed