FIELD: chemistry.
SUBSTANCE: invention relates to compounds of formula (A), where the whole of (A), except X, is denoted as MR36G-NR1R2-S; R1 is a linear or branched (C1-C10)-alkyl; R2 is hydrogen; R3 is a YR group. Y is oxygen, R is a linear or branched (C1-C6)-alkyl, provided that R3 is not O-CH3; X is hydrogen, a -S-R4-W radical or a MR36G-NR1R2-S radical, where R4 is (C1-C8)-alkyl, -(CH2)n-C(O)-NH-, or -(CH2)n-NH-C(O)-, where n is an integer ranging from 1 to 8; and W is naltrindole, as well as pharmaceutically acceptable salts. The invention also relates to a pharmaceutical composition based on said compounds for preparing a medicinal agent for curing pain, as well as use of said compounds to prepare a medicinal agent for curing pain.
EFFECT: more effective use of the compounds.
9 cl, 6 tbl, 4 dwg, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
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| NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS | 2009 |
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|
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| SYNTHETIC PEPTIDE AMIDES | 2007 |
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| BICYCLO-3,1,1-HEPTANE-SUBSTITUTED BENZIMIDAZOLONE- AND QUINAZOLINONE-DERIVATIVES AS AGONISTS OF HUMAN ORL1 RECEPTORS | 2004 |
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| 4-HYDROXYBENZOMORPHAN | 2005 |
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| COMPOSITIONS COMPRISING TRAMADOL AND CELECOXIB FOR TREATING PAIN | 2010 |
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