COMPOSITIONS COMPRISING TRAMADOL AND CELECOXIB FOR TREATING PAIN Russian patent published in 2019 - IPC A61K31/15 A61K31/85 A61K31/135 A61K31/415 A61K31/635 A61P25/00

Abstract RU 2707752 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to the pharmaceutical industry and is a pharmaceutical composition for treating pain, comprising a combination of (rac)-tramadol HCl and celecoxib in neutral form, wherein molar ratio (rac)-tramadol HCl to neutral celecoxib ranges from 1:1 to 3:1, wherein the pain is thermal hyperalgesia in the postoperative pain model.

EFFECT: invention provides a synergetic effect on the treatment of thermal hyperalgesia in the postoperative pain model.

3 cl, 1 dwg, 2 tbl, 1 ex

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RU 2 707 752 C2

Authors

Portilo Salido, Enrike

Videla Ses, Sebastiya

Dates

2019-11-29—Published

2010-10-15—Filed