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2 427 367

(13)

(51)

IPC

A61K31/205(2006-01-01)

G01N33/50(2006-01-01)

(21) (22)

Application

2010110403/15, 2010-03-18

(24)

Start date

2010-03-18

(22)

Actual filing date

2010-03-18

(45)

Published

2011-08-27

(72)

Inventor

Lemeshko Elena KhalimovnaVerlan Nadezhda VadimovnaKolesnichenko Larisa Stanislavovna

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Dopolnitel'Nogo Professional'Nogo Obrazovanija Gosudarstvennyj Institut Usovershenstvovanija Vrachej Federal'Nogo Agentstva Po Zdravookhraneniju I Sotsial'Nomu Razvitiju"

METHOD OF PREDICTING EFFICIENCY OF TREATMENT OF PATIENTS WITH CHRONIC BRAIN ISCHEMIA AND TYPE 2 DIABETES MELLITUS WITH PHARMACOLOGIC PREPARATION MILDRONAT Russian patent published in 2011 - IPC A61K31/205 G01N33/50

Abstract RU 2427367 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to pharmacotherapy and deals with method of predicting efficiency of treatment of patients with chronic brain ischemia and type 2 diabetes mellitus with pharmacologic preparation mildronate. Essence of method lies in determining in patient's blood erythrocytes activity of glutathione peroxidase (GPO). If values of GPO activity are lower than 23.7±2.23 nmol/min per 1 mg of protein, efficient treatment with mildronat is predicted. If values of GPO activity are higher than said value, treatment with mildronate is predicted to be inefficient.

EFFECT: method application provides possibility of individual prediction of efficiency of treatment with mildronat of patients with chronic brain ischemia and diabetes mellitus.

2 tbl, 2 ex

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RU 2 427 367 C1

Authors

Lemeshko Elena Khalimovna

Verlan Nadezhda Vadimovna

Kolesnichenko Larisa Stanislavovna

Dates

2011-08-27—Published

2010-03-18—Filed