STAPHYLOCOCCUS HOMINIS KLP-1 STRAIN PRODUCING LOW-MOLECULAR PEPTIDE COMPOUNDS INHIBITING GRAM-POSITIVE BACTERIA DEVELOPMENT Russian patent published in 2011 - IPC C12N1/20 C07K2/00 C12P21/00 C12R1/44 

FIELD: medicine.

SUBSTANCE: Staphylococcus hominis KLP-1 strain is recovered from a clinical material in screening of coagulase-negative staphylococci strains for ability to produce low-molecular antibacterial peptides. The strain is deposited in Tarasevich State Research Institution of Standardisation and Control of Medical Biological Preparations, No. 284. The antibacterial action is shown concerning the bacteria of the following species: Arthrobacter, Bacillus, Enterococcus, Micrococcus, Mycobacterium, Rhodococcus, Staphylococcus, Streptococcus. The low-molecular antibacterial peptide yield makes 1024000 EA in 1 l of the medium.

EFFECT: strain cultured on a nutrient fluid is characterised by higher yield of low-molecular peptide antibacterial compounds inhibiting gram-positive bacteria growth.

1 dwg, 1 tbl, 2 ex