METHOD OF TREATING ASCITIC CARCINOMA Russian patent published in 2016 - IPC A61K31/535 A61K31/711 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, specifically to oncology, and can be used for treating ascitic carcinoma. For this purpose tumour-bearing mice of CBA line weighing 20-35 g, carrying developed ascites, are parenterally administered cytostatic cyclophosphan for 0, 36, 72 hours each time in a dose of 100 mg/kg, and 18, 54, 90 hours after each injection of cyclophosphan, respectively. Also tumour-bearing mice are intraperitoneallly administered a DNA preparation, consisting of a composition of native human double-stranded DNA preparations in a dose of 3.0 mg and a mixture of native and cross-linked double-stranded DNA of salmon sperm at a ratio of 5:3 in a dose of 3 mg overall in an amount of 6.0 mg per injection, regardless of weight of tumour-mice.

EFFECT: invention provides higher clinical effectiveness in ascitic carcinoma, which consists in prevention of occurrence of secondary ascites due to developed scheme of administration of cyclophosphan and DNA preparations.

3 cl, 1 tbl, 7 dwg