FIELD: medicine.
SUBSTANCE: coagulation profile parameters are evaluated: fibrinolytic activity (FA), activated partial thromboplastin time (APTT), fibrin split products (D-Dimers) and international normalised ratio (INR). It is followed by calculating an integral coagulation factor (ICF) by formula: ICF=0.06FA+0.25INR+0.08 D-Dimer+0.54 APTT+6.54 where ICF is integral coagulation factor, FA is fibrinolytic activity (min.), INR is international normalised ratio (unit), D-Dimer is fibrin split products (ng/ml), APTT is activated partial thromboplastin time (sec.). The value ICF≥1 refers to a high risk, while the value ICF<1 - to a low risk.
EFFECT: application of the method enables evaluating a degree of risk of gestational thrombogenic complications that makes it possible to plan and control therapeutic actions aimed to normalise blood circulation in the mother-placenta-foetus system.
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Authors
Dates
2011-09-20—Published
2010-07-15—Filed