COMPOSITIONS FOR TREATING SYSTEMIC MASTOCYTOSIS Russian patent published in 2011 - IPC A61K31/553 A61K31/502 A61P35/00

Abstract RU 2429848 C2

FIELD: medicine.

SUBSTANCE: application involves a combination of AMN107 and PKC412 tyrosine kinase inhibitors for preparing a therapeutic agent for treating systemic mastocytosis (SM), including associated with oncogenic mutation KIT-D816V. The use of the invention enables higher clinical effectiveness of treating SM due to synergetic mast cell growth inhibition under action of the AMN107 and PKC412 combination.

EFFECT: higher efficacy of the composition.

3 cl, 3 tbl, 17 dwg, 2 ex

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RU 2 429 848 C2

Authors

Falent Peter

Dates

2011-09-27—Published

2006-07-19—Filed