FIELD: medicine.
SUBSTANCE: invention can be used for treatment dependent from kinase KIT diseases which are characterised by mutant forms of kinase KIT. A mutant of kinase KIT is identified and a bond A is entered, inhibiting the mutant form of kinase KIT.
EFFECT: invention use allows treating diseases dependent from kinase KIT at the expense of suppression of the alarm cascade of this enzyme leading to superfluous proliferation of cells.
13 cl, 1 dwg, 1 ex, 1 tbl
| Title |
Year |
Author |
Number |
| INHIBITORS OF KIT KINASE MUTANT FORM |
2004 |
- Bukhdunger Ehlizabet
- Fabbro Doriano
|
RU2405553C1 |
| METHOD FOR OPTIMISING IMANITIB THERAPY OF PROLIFERATIVE DISEASES MEDIATED BY THYROSINE KINASE KIT RECEPTOR |
2009 |
- Jan'Fehn Van
- Ehlizabet Verle
|
RU2537223C2 |
| ADMINISTRATION OF MIDOSTAURIN FOR TREATING GASTROINTESTINAL STROMAL TUMOURS |
2005 |
|
RU2410098C2 |
| PYRIMIDYLAMINOBENZAMIDE DERIVATIVES FOR NEUROFIBROMATOSIS |
2006 |
|
RU2450814C2 |
| COMPOUNDS AND METHODS FOR KINASE MODULATION AND INDICATIONS FOR THEIR USE |
2013 |
- Vu Guosyan
- Chan Katrina
- Eving Todd
- Ibrakhim Prabkha N.
- Lin Dzhek
- Nespi Marika
- Spevak Vejn
- Chzhan In
|
RU2666146C2 |
| COMPOSITIONS AND METHODS OF TREATING KIT- AND PDGFRα-MEDIATED DISEASES |
2020 |
- Kim, Dzhozef, L.
- Dajnin, Tomas, A.
- Guzi, Timoti
|
RU2817354C2 |
| PAN-KIT KINASE INHIBITOR HAVING QUINOLINE STRUCTURE AND ITS USE |
2018 |
- Lyu, Tszin
- Lyu, Tsinsun
- Vu, Yun
- Van, Bejlej
- Tsi, Tszypin
- Tszou, Fenmin
- Lyu, Tsinvan
- Van, Venchao
- Chen, Chen
- Van, Tszyuntsze
- Van, Li
|
RU2789405C2 |
| COMPOSITIONS FOR TREATING SYSTEMIC MASTOCYTOSIS |
2006 |
|
RU2429848C2 |
| METHOD FOR ANALYSIS OF SOMATIC MUTATIONS IN BRAF, NRAS AND KIT GENES USING LNA-BLOCKING MULTIPLEX PCR AND SUBSEQUENT HYBRIDIZATION WITH OLIGONUCLEOTIDE BIOLOGICAL MICROCHIP (BIOCHIP) |
2017 |
- Emelyanova Marina Aleksandrovna
- Zasedatelev Aleksandr Sergeevich
- Nasedkina Tatyana Vasilevna
|
RU2674338C1 |
| COMPOSITIONS AND METHODS FOR TARGET ELIMINATION OF MUTATION ESCAPE IN TARGET CANCER THERAPY |
2008 |
- Ehjpelian Dehvid
- Frantsuzoff Aleks
- Rodell Timoti K.
|
RU2505313C2 |
