METHOD OF ESTIMATING ANTIOXIDANT FUNCTION OF LIPIDS OF MEMBRANES OF PERIPHERAL BLOOD ERYTHROCYTES IN PREGNANT WOMEN DURING HERPES-VIRUS INFECTION EXACERBATION Russian patent published in 2011 - IPC G01N33/49 

Abstract RU 2430369 C2

FIELD: medicine.

SUBSTANCE: claimed is method of diagnosing antioxidant function of membranes of erythrocytes in case of exacerbation of herpes-viral infection. Method lies in determination of superoxide dismutase concentration and titre of antibodies to herpes virus by method of immunosorbent assay (ELISA) of peripheral blood in pregnant women after exacerbation of herpes-virus infection. If superoxide dismutase concentration is 297.63±13.16 Unit/gHb (control - 386.77±13.12 Unit/gHb), titre of antibodies to herpes virus in peripheral blood of pregnant woman constituted 1:3200. If titre of antibodies is 1:6400, superoxide dismutase concentration decreased to 243.85±7.71 Unit/gHb (control - 386.77±13.12 Unit/gHb; p<0.001).

EFFECT: reduction of superoxide dismutase concentration in erythrocytes of peripheral blood in pregnant women during exacerbation of herpes-virus infection predicts reduction of protective reaction of toxic impact of lipid peroxidation on membranes of erythrocytes, increasing risk of their destruction.

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RU 2 430 369 C2

Authors

Lutsenko Mikhail Timofeevich

Andrievskaja Irina Anatol'Evna

Dates

2011-09-27Published

2009-06-29Filed