FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry and medicine, and concerns a lachrymal substitute preparation which can be used for local therapy in an ocular surface disease. The invention has a composition (g/l): hydroxypropyl methylcellulose 2.5-5.0; disodium phosphate 5.5-16.5; sodium dihydrogen phosphate 0.8-1.5; sodium chloride 2.0-8.0; disodium edetate 0.1-0.5; benzalkonium chloride 0.03-0.09; dextrane 0.5-1.5; water for injections up to 1 l. The composition has the balanced proportions providing the pH value within 6.5 to 7.8, contains a polymeric composition containing hydroxypropyl methylcellulose and dextrane. As dextrane, either dextrane 40, or dextrane 60, or dextrane 70 is used.
EFFECT: invention provides ocular surface moistening that allows relieving or eliminating irritation symptoms caused by the ocular surface disease.
1 tbl, 2 ex
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Authors
Dates
2011-10-20—Published
2010-08-17—Filed