FIELD: medicine.
SUBSTANCE: method is implemented by introducing a composition containing an effective amount of interfering RNA of the length of 19-27 nucleotides, and a pharmaceutically acceptable carrier wherein interfering RNA contains a sense nucleotide chain, and an antisense nucleotide chain wherein a complementary™ site makes at least 19 continuous nucleotides. There are also presented methods of treating a TNF-α related condition in a subject in need thereof, and a composition for treating the TNF-α related eye condition.
EFFECT: invention may be effectively used in treating the patients suffering a TNF-α related condition or having a risk of such developing condition.
23 cl, 1 dwg, 2 tbl, 1 ex
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Authors
Dates
2012-12-10—Published
2007-05-17—Filed