METHOD OF OBTAINING RADIOPHARMACEUTICAL FOR RADIONUCLIDE THERAPY Russian patent published in 2011 - IPC A61K51/00 A61K103/10 A61J3/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to method of obtaining preparations, labelled with rhenium-188 radionuclide, and can be used for obtaining radiopharmaceuticals, used in radionuclide therapy. Method lies in obtaining sterile solution, which consists of ligand, reducer and antioxidant, into which later non-radioactive rhenium in form of sodium perenate (NaReO₄) is introduced. Obtained solution is neutralized, filtered, frozen and liophilically dried with further introduction of radioactive rhenium-188 (Na¹⁸⁸ReO₄) with reaction of complex-formation of ¹⁸⁸Re with ligand.

EFFECT: invention makes it possible to obtain sterile radiopharmaceutical, time of preparation of which is reduced to 30-60 minutes due to simplification of technological cycle to one stage.

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