FIELD: chemistry.
SUBSTANCE: invention relates to a radiopharmaceutical agent for diagnosing or treating (therapy) skeletal bone injury, containing a complex of zoledronic acid with 99mtechnetium or 188rhenium isotopes, zoledronic acid, tin halide or possibly an antioxidant - ascorbic or gentisic acid. The invention also relates to a method of preparing said radiopharmaceutical agent, involving mixing a lyophilisate, obtained by mixing a zoledronic acid solution and a solution of tin dichloride in hydrochloric acid in an inert gas atmosphere and adding a metal hydroxide, with a salt of a metal from the group of isotopes and a radionuclide solution.
EFFECT: more effective use of the compounds.
4 cl, 2 ex, 14 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCING A RADIOPHARMACEUTICAL PREPARATION FOR THE DIAGNOSIS AND TREATMENT OF BONE LESIONS OF THE SKELETON IN ONCOLOGICAL DISEASES BASED ON THE COMPLEX OF ZOLEDRONIC ACID WITH THE ISOTOPE OF RHENIUM-188 | 2022 |
|
RU2792618C1 |
| LYOPHILIZATE FOR OBTAINING DIAGNOSTIC RADIOPHARMACEUTICAL DRUG BASED ON RADIONUCLIDE Tc | 2022 |
|
RU2799325C2 |
| METHOD AND FORMULATION FOR PRODUCING 99m TC LABELLED 5-THIO-D-GLUCOSE AGENT FOR RADIONUCLIDE DIAGNOSIS | 2014 |
|
RU2568888C1 |
| COMPOSITION AND METHOD FOR PRODUCTION OF 99M TC LABELLED 5-THIO-D-GLUCOSE AGENT FOR RADIONUCLIDE DIAGNOSIS | 2016 |
|
RU2644744C1 |
| STABILISED COMPOSITIONS OF TECHNETIUM-99m (Tc) | 2005 |
|
RU2403067C2 |
| OSTEOTROPIC RADIOPHARMACEUTICALS FOR PET IMAGING | 2014 |
|
RU2614235C2 |
| RADIOPHARMACEUTICAL COMPOSITION FOR TREATMENT OF PAIN IN INFLAMMATORY DISEASES OF JOINTS | 2017 |
|
RU2662088C1 |
| METHOD OF PREPARING REAGENT FOR PRODUCING TECHNETIUM-99m LABELLED DOXORUBICIN | 2014 |
|
RU2563134C1 |
| METHOD OF OBTAINING REAGENT FOR PREPARATION OF TECHNECIUM 99-m LABELLED NANOCOLLOID BASED ON GAMMA-OXIDE OF ALUMINIUM | 2013 |
|
RU2512595C1 |
| REAGENT FOR PRODUCING OF RADIOPHARM PREPARATION AND A METHOD OF REAGENT PRODUCING | 0 |
|
SU1787035A3 |
