AMINE COMPOUND AND ITS APPLICATION IN MEDICINAL PURPOSES Russian patent published in 2011 - IPC C07C217/64 C07C255/54 C07C323/32 C07F9/09 A61P37/06 A61P37/08 A61K31/137 A61K31/165 A61K31/222 A61K31/277 C07C323/43 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to compound, represented by the following formula (I), where R represents hydrogen atom or P(=O)(OH)₂, X represents oxygen atom or sulphur atom, Y represents CH₂CH₂ or CH=CH, R₁ represents trifluoromethyl, difluoromethyl or cyano, R₂ represents alkyl, which has 1-4 carbon atoms, and optionally substituted with hydroxyl group (groups) or halogen atom (atoms), R₃ and R₄ can be similar or different, and each represents hydrogen atom or alkyl, which has 1-4 carbon atoms, and n=5-8, or its pharmaceutically acceptable acid-additive salt. Invention also relates to 2-amino-2-[2-(4-heptyloxy-3-trifluoromethylphenyl)ethyl]propan-1,3-diol or its hydrochloride and pharmaceutical composition, containing said compounds.

EFFECT: elaboration of pharmaceutical composition, applied for treatment or prevention of autoimmune diseases, prevention or suppression of resistance or acute rejection or chronic rejection of organ or tissue transplant; treatment or prevention of graft-versus-host disease (GvH) resulting from transplantation of bone marrow; or treatment or prevention of allergic diseases.

16 cl, 39 ex