AMINODIHYDROTHIAZINE DERIVATIVES SUBSTITUTED BY CYCLIC GROUP Russian patent published in 2013 - IPC C07D279/06 C07D417/12 C07D417/14 A61K31/541 A61P25/28 

Abstract RU 2476430 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a compound of formula

wherein the cycle A represents a carbocyclic group or a heterocyclic group; R1 means (i) lower alkyl optionally substituted by halogen, (ii) lower alkenyl, (iii) lower alkynyl or (iv) a carbocyclic group; each of R3a, R3b, R3c and R3d independently means hydrogen, halogen, lower alkyl optionally substituted by halogen, lower alkenyl, carbocyclyl - lower alkoxy or a carbocyclic group, or R3a and R3b or R3c and R3d can form C3-C10 cycloalkane ring together with an adjoining carbon atoms and can form oxo; a pharmaceutically acceptable salt or solvate of said compound effective in treating the diseases caused by β-amyloid protein production, secretion and/or fixation.

EFFECT: preparing the pharmaceutically acceptable salt or solvate effective in treating the diseases caused by β-amyloid protein production, secretion and/or fixation.

18 cl, 139 tbl, 4 ex

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RU 2 476 430 C2

Authors

Tamura Juusuke

Suzuki Sindzi

Tada Jukio

Jonezava Sudzi

Fudzikosi Tiaki

Matsumoto Sae

Koorijama Juudzi

Ueno Tatsukhiko

Dates

2013-02-27Published

2008-04-23Filed