AMINE DERIVATIVE POSSESSING ANTAGONISTIC ACTIVITY WITH RESPECT TO RECEPTOR NPY Y5 Russian patent published in 2011 - IPC C07C311/05 C07C317/36 C07D213/38 C07D263/58 C07D277/82 A61K31/18 A61K31/40 A61K31/415 A61K31/4164 A61K31/423 A61K31/428 A61K31/44 A61P3/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to compound of formula (I), its pharmaceutically acceptable salt or solvate, in which R¹ represents lower alkyl, Y represents -S(O)n-, where n equals 1 or 2, R² represents hydrogen or lower alkyl, R¹ and R² together can form lower alkylene, R⁷ represents hydrogen, X represents group of formula: [formula 2], where R³, R⁴, R⁵ and R⁶ each independently represent hydrogen, group of formula: [formula 3] represents C₅-C₆-cvycloalkylene, p and q each independently equals integer number from 0 to 2, p or q is not equal 0, and Z represents optionally substituted phenyl, optionally substituted pyridyl, optionally substituted pyridasinyl, optionally substituted pyrasolyl, optionally substituted indanyl, optionally substituted benzothiazolyl, optionally substituted benzoxazolyl, optionally substituted thiazolopyridyl, optionally substituted oxazolopyridyl, optionally substituted benzimidasolyl, optionally substituted benzoxazinonyl, optionally substituted chinolyl, optionally substituted isochinolyl, optionally substituted benzoxazolinonyl, optionally substituted benzoxazolinonyl or optionally substituted ftalazinyl.

EFFECT: obtaining pharmaceutical composition, obtaining antagonistic activity with respect to receptor NPY Y5, based on said compounds.

14 cl, 1 tbl, 6 ex