SULFONAMIDE COMPOUND Russian patent published in 2003 - IPC

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to sulfonamide compound of the where R¹ means alkyl, alkenyl, alkynyl; A means optionally substituted heterocyclic group excepting for benzimidazolyl, indolyl, 4,7-dihydrobenzimidazolyl and 2,3-dihydrobenzoxazinyl; X means alkylene, oxa-group, oxa-(lower)-alkylene; R² means optionally substituted aryl, substituted biphenyl, its salt and pharmaceutical composition comprising this compound. The proposed sulfonamide compound is effective in treatment of diseases since it is able to decrease blood glucose level, to inhibit activity of cGMP-PDE (phosphodiesterase) and especially activity of PDE-V, to exhibit relaxing effect with respect to smooth muscles. Also, it exhibits bronchodilating activity, vasodilating activity, activity associated with suppression of smooth muscle cells and antiallergic activity. EFFECT: valuable medicinal properties of compound. 8 cl, 1 tbl, 399 ex