METHOD OF PRODUCING 1-ALKYL-2-ALKYL(CYCLOALKENYL, BENZYL)CYCLOPROPANOLS Russian patent published in 2011 - IPC C07C35/21 C07C29/36 

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing 1-alkyl-2-alkyl(cycloalkenyl, benzyl)cyclopropanols of general formula (I):

R=C₆H₁₃, R'=CH₃, C₂H₅, C₄H₉,

, ;

which can be used in fine organic synthesis, particularly synthesis of biologically active compounds, having pyrethroid, acaricide, pesticide, growth-regulating, fungicide and anti-bacterial activity. The method involves catalytic reaction of olefin with an organometallic compound and an ester. The organometallic compound used is ethylaluminium dichloride (EtAlCl₂). Reaction of α-olefin of general formula R-CH=CH₂, where R=C₆H₁₃, ,

with an ester of formula R'CO₂R", where R'=CH₃, C₂H₅, C₄H₉; R"=Me, Et and EtAlCl₂ is carried out in the presence of Mg (powder) and a Cp₂ZrCl₂ catalyst in molar ratio R-CH=CH₂: R'CO₂R":EtAlCl₂:Mg:Cp₂ZrCl₂=10:10:(20-30):(10-14):(0.8-1.2) in an argon atmosphere at temperature 20-22°C and atmospheric pressure for 8-12 hours.

EFFECT: method enables to obtain desired products with high regioselectivity.

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