FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to pharmaceutical field and deals with composition with delayed release, which does not contain gelatin, contains polymer of lactic and glycolic acids with ratio of average molecular weight and average numerical molecular weight about 1.90 or less or its salt and physiologically active substance, where polymer of lactic and glycolic acids has average molecular weight from 8000 to 15000 and molar ratio of lactic acid to glycolic acid constitutes from 70:30 to 80:20, and physiologically active substance represents peptide of formula: 5-oxo-Pro-His-Trp-Ser-Tyr-DLeu-Leu-Arg-Pro-NH-C2H5, or its acetate. In addition, invention describes method of obtaining said composition.
EFFECT: invention makes it possible to suppress high initial release of medication and, in such way, ensure stable rate of release during approximately one month.
10 cl, 4 tbl, 9 ex
