FIELD: medicine.
SUBSTANCE: invention relates to devices and methods with increased sensitivity in carrying out diagnostics, for instance, optic biopsy. Method of determining area of interest includes providing one or more ionic probes suitable for demonstration of avalanche effect with shift of emitted irradiation to higher frequency, impact on ionic probe(s) by activation energy and determination of one or more areas with higher concentration of ionic probe(s) on the basis of emission, connected, at least, partially with avalanche effect. System ensures determination of area of interest in accordance with the method.
EFFECT: application of invention makes it possible to considerably reduce or eliminate intensity of background signal from ionic probes, distributed in lower concentration throughout volume of measurements, also in application of invention, in fact, there is no background autofluorescence of surrounding healthy tissue.
16 cl, 5 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR CREATING HIGHLY EFFECTIVE UPCONVERSION LUMINESCENCE OF YTTERBIUM OXIDE COMPLEXES WITH GOLD NANOPARTICLES | 2021 |
|
RU2779620C1 |
| PRODUCT AUTHENTICATION METHOD | 2000 |
|
RU2261479C2 |
| DETECTOR WITH REDUCED NOISE IN FLUORESCENCE RANGE | 2018 |
|
RU2819048C1 |
| DETECTOR WITH REDUCED NOISE IN FLUORESCENCE BAND | 2018 |
|
RU2738311C1 |
| LUMINESCENT COMPOUND BASED ON RARE EARTH METAL IONS | 2020 |
|
RU2754001C1 |
| IMPROVED RAMAN SCATTER WITH HIGH ACCEPTANCE CONE, RESOLUTION, TRANSMISSION, QUANTUM EFFICIENCY AND BACKGROUND REDUCTION | 2011 |
|
RU2563770C2 |
| METHOD FOR NON-INVASIVE MONITORING OF A FLUORESCENT INDICATOR AGENT WITH A LABELED ATOM WITH BACKGROUND SEPARATION CORRECTIONS | 2018 |
|
RU2720132C1 |
| BOROPHOSPHATE PHOSPHOR AND LIGHT SOURCE | 2011 |
|
RU2583023C2 |
| LUMINESCENT PHOTOVOLTAIC GENERATOR AND WAVEGUIDE TO BE INCORPORATED WITH PHOTOVOLTAIC GENERATOR | 2009 |
|
RU2515182C2 |
| TESTING DEVICE AND METHOD OF ITS USE | 2017 |
|
RU2701875C1 |
