-5-4-CHLOROPHENYL-3-[2-(4-CHLOROPHENYL)ETHENYL]-2-OXASPIRO[5,6]DODEC-3-EN-1-ONE, HAVING ANALGESIC ACTIVITY Russian patent published in 2011 - IPC C07D311/96 A61K31/352 A61P29/00 

Abstract RU 2435767 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry and specifically to a novel biologically active compound (E)-5-(4-chlorophenyl)-3-[2-(4-chlorophenyl)ethenyl]-2-oxaspiro[5.6]dodec-3-en-1-one of formula (I), having analgesic activity and which can be used in different organic syntheses.

EFFECT: wider range of agents having effect on a living organism.

1 cl, 1 tbl, 2 ex

Similar patents RU2435767C1

Title Year Author Number
METHOD OF PRODUCING 5-ARYL-3-PHENYL-2-OXASPIRO[5,6]DODEC-3-EN-1-ONES, EXHIBITING ANALGESIC ACTIVITY 2011
  • Kirillov Nikolaj Fedorovich
  • Gavrilov Aleksandr Gennad'Evich
  • Makhmudov Ramiz Ragibovich
  • Mardanova Ljudmila Gennad'Evna
RU2461555C1
ETHYL2-ETHYL-2-(1-OXO-5-PHENYL-2-OXASPIRO[5,5]UNDEC-3-EN-3-YL)BUTANOATE, HAVING ANALGESIC ACTIVITY AND SYNTHESIS METHOD 2010
  • Kirillov Nikolaj Fedorovich
  • Makhmudov Ramiz Ragibovich
  • Nikiforova Elena Aleksandrovna
  • Mardanova Ljudmila Gennad'Evna
RU2453542C1
(E)-4'-ARYL-7'-ARYLMETHYLENE-4',5',6',7'-TETRAHYDRO-2'H-SPIRO[CYCLOALKANE-1,3'-CYCLOPENTA[b]PYRAN]-2'-ONES, EXHIBITING ANALGESIC ACTIVITY AND SYNTHESIS METHOD THEREOF 2010
  • Kirillov Nikolaj Fedorovich
  • Makhmudov Ramiz Ragibovich
  • Gavrilov Aleksandr Gennad'Evich
  • Mardanova Ljudmila Gennad'Evna
RU2455300C2
METHOD FOR PRODUCING METHYL 1-[3-(CYCLOHEXYLCARBAMOYL)-2-OXOCHROMAN-4-YL] CYCLOPENTACARBOXYLATE SHOWING ANALGESIC ACTIVITY 2013
  • Kirillov Nikolaj Fedorovich
  • Nikiforova Elena Aleksandrovna
  • Makhmudov Ramiz Ragibovich
  • Mardanova Ljudmila Gennad'Evna
RU2549357C2
USE OF N-[1-ARYL-3-OXO-2-AZASPIRO[3.5]NONAN-2-YL]BENZAMIDES AS ANALGESIC MEDICINAL PRODUCTS 2023
  • Nikiforova Elena Aleksandrovna
  • Zverev Dmitrii Pavlovich
  • Makhmudov Ramiz Ragibovich
  • Uchuskin Maksim Grigorevich
  • Mendogralo Elena Iurevna
  • Makarov Anton Sergeevich
  • Rubtsov Aleksandr Evgenevich
RU2810704C1
METHOD FOR PRODUCING METHYL 1-[(1,3-DIOXO-2,3-DIHYDRO-1H-INDEN-2-YL)-(4-METHYLPHENYL)METHYL]CYCLOHEXANE CARBOXYLATE SHOWING ANALGESIC ACTIVITY 2013
  • Kirillov Nikolaj Fedorovich
  • Nikiforova Elena Aleksandrovna
  • Makhmudov Ramiz Ragibovich
  • Mardanova Ljudmila Gennad'Evna
RU2549566C2
USE OF 1'-ARYLDISPIRO[CYCLOALKANE-1,3'-AZETIDINE-2',3''-INDOLINE]-2'',4'-DIONES AS ANALGESICS 2023
  • Nikiforova Elena Aleksandrovna
  • Zverev Dmitrii Pavlovich
  • Makhmudov Ramiz Ragibovich
  • Uchuskin Maksim Grigorevich
  • Mendogralo Elena Iurevna
  • Makarov Anton Sergeevich
  • Rubtsov Aleksandr Evgenevich
  • Sergeeva Serafima Valerevna
RU2809008C1
METHOD OF PRODUCING 5-ARYL-2-METHYL-1,3-DIOXO-2-AZASPIRO[5,5] UNDECANE-4-CARBONITRILES AND AGENT EXHIBITING ANALGESIC ACTIVITY 2011
  • Kirillov Nikolaj Fedorovich
  • Makhmudov Ramiz Ragibovich
  • Nikiforova Elena Aleksandrovna
  • Mardanova Ljudmila Gennad'Evna
RU2455284C1
USE OF N-[2-(1-OXO-3,5-DIPHENYL-2-AZASPIRO[5.5]UNDEC-3-EN-2 IL)PHENYL]-3-BROMOBENZAMIDE AS ANALGESIC 2023
  • Nikiforova Elena Aleksandrovna
  • Zverev Dmitrii Pavlovich
  • Makhmudov Ramiz Ragibovich
  • Uchuskin Maksim Grigorevich
  • Mendogralo Elena Iurevna
  • Makarov Anton Sergeevich
  • Rubtsov Aleksandr Evgenevich
RU2808999C1
USE OF 2-(4-BROMOPHENYL)-3-(2-PHENYLETHENYL)-2-AZASPIRO[3.5]NONAN-1-ONE AS AN AGENT WITH ANALGESIC ACTIVITY 2023
  • Uchuskin Maksim Grigorevich
  • Mendogralo Elena Iurevna
  • Makarov Anton Sergeevich
  • Nikiforova Elena Aleksandrovna
  • Rubtsov Aleksandr Evgenevich
  • Zverev Dmitrii Pavlovich
RU2808988C1

RU 2 435 767 C1

Authors

Kirillov Nikolaj Fedorovich

Gavrilov Aleksandr Gennad'Evich

Makhmudov Ramiz Ragibovich

Mardanova Ljudmila Gennad'Evna

Dates

2011-12-10Published

2010-07-05Filed