FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing 2-ethyl-2-(1-oxo-5-phenyl-2-oxaspiro[5,5]undec-3-en-3-yl)butanoate of formula (I) 
The method is realised by boiling methyl ether of 1-bromocyclohexane carboxylic acid with zinc and ethyl 2,2-diethyl-3-oxo-5-phenylpent-4-enoate in a benzene-ethyl acetate - HMPA medium (10:5:1) for 4 hours.
EFFECT: method of obtaining a novel compound having analgesic activity.
2 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| USE OF N-[2-(1-OXO-3,5-DIPHENYL-2-AZASPIRO[5.5]UNDEC-3-EN-2 IL)PHENYL]-3-BROMOBENZAMIDE AS ANALGESIC | 2023 |
|
RU2808999C1 |
| METHOD OF PRODUCING 5-ARYL-3-PHENYL-2-OXASPIRO[5,6]DODEC-3-EN-1-ONES, EXHIBITING ANALGESIC ACTIVITY | 2011 |
|
RU2461555C1 |
| USE OF N-[1-ARYL-3-OXO-2-AZASPIRO[3.5]NONAN-2-YL]BENZAMIDES AS ANALGESIC MEDICINAL PRODUCTS | 2023 |
|
RU2810704C1 |
| -5-4-CHLOROPHENYL-3-[2-(4-CHLOROPHENYL)ETHENYL]-2-OXASPIRO[5,6]DODEC-3-EN-1-ONE, HAVING ANALGESIC ACTIVITY | 2010 |
|
RU2435767C1 |
| METHOD FOR PRODUCING METHYL 1-[3-(CYCLOHEXYLCARBAMOYL)-2-OXOCHROMAN-4-YL] CYCLOPENTACARBOXYLATE SHOWING ANALGESIC ACTIVITY | 2013 |
|
RU2549357C2 |
| METHOD OF PRODUCING 5-ARYL-2-METHYL-1,3-DIOXO-2-AZASPIRO[5,5] UNDECANE-4-CARBONITRILES AND AGENT EXHIBITING ANALGESIC ACTIVITY | 2011 |
|
RU2455284C1 |
| (E)-4'-ARYL-7'-ARYLMETHYLENE-4',5',6',7'-TETRAHYDRO-2'H-SPIRO[CYCLOALKANE-1,3'-CYCLOPENTA[b]PYRAN]-2'-ONES, EXHIBITING ANALGESIC ACTIVITY AND SYNTHESIS METHOD THEREOF | 2010 |
|
RU2455300C2 |
| METHOD FOR PRODUCING METHYL 1-[(1,3-DIOXO-2,3-DIHYDRO-1H-INDEN-2-YL)-(4-METHYLPHENYL)METHYL]CYCLOHEXANE CARBOXYLATE SHOWING ANALGESIC ACTIVITY | 2013 |
|
RU2549566C2 |
| USE OF 2-(4-BROMOPHENYL)-3-(2-PHENYLETHENYL)-2-AZASPIRO[3.5]NONAN-1-ONE AS AN AGENT WITH ANALGESIC ACTIVITY | 2023 |
|
RU2808988C1 |
| USE OF 1'-ARYLDISPIRO[CYCLOALKANE-1,3'-AZETIDINE-2',3''-INDOLINE]-2'',4'-DIONES AS ANALGESICS | 2023 |
|
RU2809008C1 |
