FIELD: medicine.
SUBSTANCE: vector carries an additional transcription unit containing a foreign gene functionally coupled with an overlying starting sequence of a virus gene (GS) of Mononegavirales order and an underlaying end sequence of a virus gene (GE) of Mononegavirales order; between the GS sequence and an initiator codon of the foreign gene and between a stop sign of the foreign gene and the GE sequence there are respectively 3'-noncoding area and 5'-noncoding area (a genome sense chain) of the virus gene of Mononegavirales order.
EFFECT: higher expression level of the protein coded by the foreign gene.
22 cl, 9 dwg, 6 tbl, 6 ex
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