METHOD OF INTRODUCTION OF PNA MOLECULE CONJUGATED WITH POSITIVE PEPTIDE, IN CYTOSOL AND/OR NUCLEUS BY PHOTOCHEMICAL INTERNALISATION (PCI) Russian patent published in 2011 - IPC C12N15/87 A61K41/00 A61K48/00 C12Q1/68 C12Q1/02 

Abstract RU 2435859 C2

FIELD: medicine.

SUBSTANCE: method provides contact of said cell with a peptide nucleic acid (PNA) molecule and a photosensitising agent and cell exposure to light at wave length effective to activate the photosensitising agent where said PNA molecule is conjugated with positive peptide. Also, there are described compositions containing such conjugated PNA molecules, the cells produced with the use of the method, and application of the method.

EFFECT: effective cell capture of peptide nucleic acid molecules conjugated with positive peptide.

37 cl, 13 dwg, 9 ex

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RU 2 435 859 C2

Authors

Khevig Ehjvinn

Fodstad Ejstejn

Beeh Sigurd

Dates

2011-12-10Published

2005-07-07Filed