METHOD OF TREATING NON-RESECTABLE SIGNET RING CELL ADENOCARCINOMA Russian patent published in 2012 - IPC A61M25/01 A61K31/14 A61K31/513 A61K31/00 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to oncology, and can be used for treatment of patients with non0resectable signet ring cell adenocarcinoma. For this purpose laparotomy is performed. Into left gastric artery installed and fixed is catheter, through which 50-70 ml of ozonised physiological solution are introduced. After 30 minutes, 1000 mg of 5-fluoracyl and 50 mg leukovorin are introduced in the same way. After that, catheter is connected with port, installed in recess, specially created in subcutaneous adipose cellular tissue and brought under skin of anterior abdominal wall, wound is sewn layer-by layer. 7 days after operation into port, installed in anterior abdominal wall, connected with catheter, 50-70 ml of ozonised physiological solution are introduced. After 30 minutes, 1000 mg of 5-fluoracyl and 50 mg leukovorin are introduced in the same way. Procedure is repeated 5 more times with 1 week interval.

EFFECT: method ensures increase of anti-tumour activity of chemical preparations at the background of non-specific stimulation of patients' immunity, achieved by introduction of ozonised physiological solution.

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