2-AMIDO-4-ARYLOXY-1-CARBONYLPYRROLIDINE DERIVATIVES AS SERINE PROTEASE INHIBITORS, PARTICULARLY NS3-NS4A HCV PROTEASE Russian patent published in 2012 - IPC C07K5/10 A61K38/55 A61P31/14 

Abstract RU 2440368 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula , which inhibit serine protease activity, particularly hepatitis C virus NS3-NS4A protease. The compounds act by inhibiting the life cycle of the hepatitis C virus, and can also be used as antiviral agents. The invention also relates to compositions containing said compounds, or for use in vivo or for administration to patient suffering from HCV infection.

EFFECT: high efficiency of using the composition.

35 cl, 5 ex

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RU 2 440 368 C2

Authors

Perni Robert B.

Kort Dzhon Dzh.

Britt Shon D.

Pitlik Janosh

Van Dri Dzhon Kh.

Dates

2012-01-20Published

2004-09-07Filed