FIELD: medicine.
SUBSTANCE: invention relates to compounds of formula
and their pharmaceutically acceptable salts, inhibiting activity of serine protease, in particular, activity of protease of hepatitis C virus HC3-HC4A. Claimed invention also relates to pharmaceutical compositions, which contain said compounds, method of inhibiting serine protease activity.
EFFECT: elimination or reduction of infection with hepatitis C virus.
27 cl, 1 tbl, 5 ex
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| DERIVATIVES OF 3-[2-(3-ACYLAMINO-2-OXO-2H-PYRIDIN-1-YL)-ACETYLAMINO]-4-OXO-PENTANE ACID AND THEIR APPLICATION AS CASPASE INHIBITORS | 2005 |
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| ISOXAZOLINES AND ISOXAZOLES, METHOD OF INHIBITION OF PLATELET AGGREGATION, PHARMACEUTICAL COMPOSITION INHIBITING PLATELET AGGREGATION | 1994 |
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| PROCESS FOR STABILIZING CRYSTALLINE ORGANIC PHOSPHITE OR PHOSPHONITE FROM EFFECT OF HYDROLYSIS, AND ORGANIC PHOSPHITE OR PHOSPHONITE STABILIZED FROM EFFECT OF HYDROLYSIS | 1993 |
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| 2-AMIDO-4-ARYLOXY-1-CARBONYLPYRROLIDINE DERIVATIVES AS SERINE PROTEASE INHIBITORS, PARTICULARLY NS3-NS4A HCV PROTEASE | 2004 |
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