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(19)

(11)

2 465 264

(13)

(51)

IPC

C07C231/20(2006-01-01)

C07D207/09(2006-01-01)

C07D403/12(2006-01-01)

A61K31/497(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2008140941/04, 2007-03-14

(24)

Start date

2007-03-14

(22)

Actual filing date

2007-03-14

(45)

Published

2012-10-27

(72)

Inventor

Perni Robert B.Chen' Min'ChzhanDzung Joung Chun'Forslund Rehjmond E.Tehnouri Dzheral'D Dzh.Bennani JussefZlokarnik GregorMal'Te Fransua

(73)

Holder

Verteks Farmas'Jutikalz Inkorporejted

DEUTERATED HEPATITIS C PROTEASE INHIBITORS Russian patent published in 2012 - IPC C07C231/20 C07D207/09 C07D403/12 A61K31/497 A61P31/12

Abstract RU 2465264 C2

FIELD: medicine.

SUBSTANCE: invention refers to a deuterium-enriched α-ketoamide compound of formula wherein: D means a deuterium atom; the values R¹-R⁵ are presented in cl.1 of the patent claim, and to a based pharmaceutical composition.

EFFECT: method improvement.

32 cl, 3 ex

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RU 2 465 264 C2

Authors

Perni Robert B.

Chen' Min'Chzhan

Dzung Joung Chun'

Forslund Rehjmond E.

Tehnouri Dzheral'D Dzh.

Bennani Jussef

Zlokarnik Gregor

Mal'Te Fransua

Dates

2012-10-27—Published

2007-03-14—Filed