FIELD: pharmacology.
SUBSTANCE: invention refers to binuclear cation nitrosyl iron complexes with natural aliphatic thiolyls with general formula [Fe2(SR)2(NO)4]SO4 where R is aliphatic ligands of natural origin.
Also there is proposed method for production of binuclear cation nitrosyl iron complex, nitrogen monoxide donor, inductor of tumor cells apoptosis, application binuclear cation nitrosyl iron complex, pharmaceutical composition and set used for treatment of oncology diseased. The technical result is EFFECT: production of binuclear cation nitrosyl iron complex possessing cytotoxic, apoptotic and NO-donor activity.
15 cl, 2 ex, 4 tbl, 7 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| BINUCLEAR NITROSYL IRON COMPLEXES WITH BENZAZEHETEROCYCLIC DERIVATIVES, WAYS OF ITS PRODUCTION | 2007 |
|
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|
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|
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|
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| SINGLE-NUCLEAR CATIONIC DINITROSYL IRON COMPLEXES, METHOD FOR PRODUCING THEM, NITROGEN MONOXIDE DONOR | 2014 |
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| USE OF NITROSYL IRON COMPLEX WITH N,N-DIETHYLTHIOUREA AS NEW NO-DONOR ANTICANCER AGENT | 2016 |
|
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| APOPTOSIS-INDUCING AGENTS AND A METHOD FOR PRODUCTION THEREOF | 2018 |
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