FIELD: medicine.
SUBSTANCE: what is offered is a binding agent of a pathogenic isoform of a prion protein containing lactoferrin. There are offered a method for detecting and a method for recovering the pathogenic isoform of the prion protein involving the stage of sample contacting with the binding agent of the pathogenic isoform of the prion protein and the stage of binded component separation from the binding agent of the pathogenic isoform of the prion protein contacting with the sample. The method for detecting additionally involves the stage of detection of the pathogenic isoform of the prion protein found in the component of the pathogenic isoform of the prion protein separated from the binding agent.
EFFECT: fast, simple and high-sensitive methods for detecting and recovering the pathogenic isoform of the prion protein without its enzymatic treatment with protease K.
6 cl, 2 dwg, 2 ex
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