FIELD: medicine.
SUBSTANCE: potentially affected tissue and adjoining histologically normal tissue are examined for a level of RHOV gene transcription. A higher level of RHOV gene transcription in potentially affected tissue in comparison with the same in adjoining histologically normal tissue serves as a diagnostic sign of non-small-cell lung cancer. A polymerase chain reaction for the purpose of RHOV gene transcription is conducted by using a set of primers having sequences SEQ ID NO: 1 and 2.
EFFECT: invention provides high-reliable diagnosis of non-small-cell lung cancer, including squamous cell carcinoma and adenocarcinoma, including at the early stage of progressing cancer transformation.
12 cl, 1 tbl, 7 ex, 2 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF NON-SMALL CELL LUNG CARCINOMA DIAGNOSTICS AND RELATED ANALYSIS SET | 2006 |
|
RU2330285C1 |
| METHOD OF EPIDERMOID LUNG CANCER DIAGNOSTICS AND RELATED SET | 2006 |
|
RU2327162C1 |
| METHOD AND TOOL FOR DIAGNOSTICS OF PULMONARY EPIDERMOID CARCINOMA | 2006 |
|
RU2324186C1 |
| METHOD OF DIAGNOSING NON-SMALL CELL LUNG CANCER AND SET FOR REALISING IT | 2007 |
|
RU2351936C1 |
| DIAGNOSTIC TECHNIQUE FOR NON-SMALL CELL CARCINOMA OF LUNG AND KIT FOR IMPLEMENTATION THEREOF | 2008 |
|
RU2390780C1 |
| METHOD OF DIAGNOSING SQUAMOUS CELL CARCINOMA OF LUNG AND KIT FOR IMPLEMENTATION THEREOF | 2014 |
|
RU2586779C2 |
| METHOD FOR DETERMINING NON-SMALL CELLS LUNG CANCER SENSITIVITY TO PREPARATIONS REACTIVATING PROTEIN p53 | 2012 |
|
RU2509808C1 |
| DIAGNOSTIC TECHNIQUE FOR CLEAR CELL RENAL ADENOCARCINOMA AND SET FOR IMPLEMENTATION THEREOF | 2009 |
|
RU2393472C1 |
| DETERMINING mRNA LEVEL REDUCTION IN GENES ITGA9, HYAL1 AND HYAL2 AS METHOD OF DIAGNOSING NON-SMALL CELL LUNG CANCER AND SET FOR ITS REALISATION | 2008 |
|
RU2403575C2 |
| DIAGNOSTIC TECHNIQUE FOR COLON CANCER AND KIT FOR IMPLEMENTING THEREOF | 2008 |
|
RU2374647C1 |
