DETERMINING mRNA LEVEL REDUCTION IN GENES ITGA9, HYAL1 AND HYAL2 AS METHOD OF DIAGNOSING NON-SMALL CELL LUNG CANCER AND SET FOR ITS REALISATION Russian patent published in 2010 - IPC G01N33/53 

Abstract RU 2403575 C2

FIELD: medicine.

SUBSTANCE: invention is claimed as application of mRNA level of genes 1TGA9, HYAL1 and HYAL2 as markers for diagnostics of epidermoid lung cancer (ELC) and lung adenocarcinoma (LA). Decreased mRNA level of said genes in supposedly affected with cancer human tissue in comparison with its level in healthy tissue serves as diagnostic marker of non-small cell lung cancer.

EFFECT: invention allows to diagnose non-small cell lung cancer of LA and ELC type with high reliability, including the earliest clinical stage of tumour disease.

3 tbl, 7 ex, 1 dwg

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RU 2 403 575 C2

Authors

Senchenko Vera Nikolaevna

Anedchenko Ekaterina Anatol'Evna

Kondrat'Eva Tat'Jana Tikhonovna

Sakharova Ol'Ga Viktorovna

Imjanitov Evgenij Naumovich

Frejdlin Irina Solomonovna

Dates

2010-11-10Published

2008-09-18Filed