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(19)

(11)

2 454 414

(13)

(51)

IPC

C07D417/14(2006-01-01)

C07D401/08(2006-01-01)

A61K31/4709(2006-01-01)

A61P25/04(2006-01-01)

A61P25/16(2006-01-01)

A61P25/22(2006-01-01)

A61P25/24(2006-01-01)

(21) (22)

Application

2009111337/04, 2007-10-19

(24)

Start date

2007-10-19

(22)

Actual filing date

2007-10-19

(45)

Published

2012-06-27

(72)

Inventor

Bui KankhDanttsman KehtiEhrnst GlenKhoush ValeriKhudzik TomasKing Megan MerfiLiu DzhieJan Dzhingbo

(73)

Holder

Astrazeneka Ab

N-(2-HYDROXYETHYL)-N-METHYL-4-(QUINOLIN-8-YL(1-(THIAZOL-4-YLMETHYL) PIPERIDIN-4-YLIDENE)METHYL)BENZAMIDE, METHOD FOR PREPARING AND APPLYING IT FOR TREATING PAIN, ANXIETY AND DEPRESSION Russian patent published in 2012 - IPC C07D417/14 C07D401/08 A61K31/4709 A61P25/04 A61P25/16 A61P25/22 A61P25/24

Abstract RU 2454414 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to N-(2-hydroxyethyl)-N-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)-piperidin-4-ylidene)methyl)benzamide, and/or their mixture, as well as to applying it in a pharmaceutical composition, a method of treating to be applied for treating pain, anxiety, depression, worried depression or Parkinson's disease. Also, the invention refers to methods for preparing N-(2-hydroxyethyl)-N-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)-piperidin-4-ylidene)methyl)benzamide and its intermediate compounds. .

EFFECT: developing the method of treating to be applied for treating pain, anxiety, depression, worried depression or Parkinson's disease.

12 cl, 1 ex

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RU 2 454 414 C2

Authors

Bui Kankh

Danttsman Kehti

Ehrnst Glen

Khoush Valeri

Khudzik Tomas

King Megan Merfi

Liu Dzhie

Jan Dzhingbo

Dates

2012-06-27—Published

2007-10-19—Filed