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(19)

(11)

2 477 719

(13)

(51)

IPC

C07D207/06(2006-01-01)

C07D401/12(2006-01-01)

C07D401/14(2006-01-01)

C07D403/14(2006-01-01)

C07D405/12(2006-01-01)

C07D409/14(2006-01-01)

C07D417/14(2006-01-01)

C07D471/04(2006-01-01)

A61K31/4025(2006-01-01)

A61P25/00(2006-01-01)

(21) (22)

Application

2010119560/04, 2008-10-14

(24)

Start date

2008-10-14

(22)

Actual filing date

2008-10-14

(45)

Published

2013-03-20

(72)

Inventor

Chekhtizkij VerngardGao ChzhunliKherst Vill'Jam Dzh.Shvink LotarShtengelin Zigfrid

(73)

Holder

Sanofi-Aventis

SUBSTITUTED N-PHENYLBIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF Russian patent published in 2013 - IPC C07D207/06 C07D401/12 C07D401/14 C07D403/14 C07D405/12 C07D409/14 C07D417/14 C07D471/04 A61K31/4025 A61P25/00

Abstract RU 2477719 C2

FIELD: chemistry.

SUBSTANCE: invention relates to substituted N-phenylbipyrrolidine carboxamides of formula , where values of R, R₁, R₂, R₃ and R₄ are given in claim 1.

EFFECT: compounds have activity which binds to the H3 ligand, which allows use thereof in pharmaceutical compositions for treating sleep disorder.

10 cl, 1 tbl, 4 dwg, 153 ex

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RU 2 477 719 C2

Authors

Chekhtizkij Verngard

Gao Chzhunli

Kherst Vill'Jam Dzh.

Shvink Lotar

Shtengelin Zigfrid

Dates

2013-03-20—Published

2008-10-14—Filed