FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to toxicology and cardiology, and deals with prevention of chronic toxic arterial hypertension and cardiopathy in experimental animals. For this purpose 1 time per day lead acetate in dose 40 mg/kg and detoxicant are simultaneously introduced to animals intragastrically. As detoxicant introduced is preparation of melatonin melaxen in dose 10 mg/kg.
EFFECT: method ensures reduction of lead cytotoxicity due to membrane-protecting and antioxidant action of melatonin.
1 tbl, 1 ex, 2 dwg
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