METHOD FOR SIMULATING CHRONIC TOXIC ARTERIAL HYPERTENSION AND CARDIOPATHY IN EXPERIMENTAL ANIMALS Russian patent published in 2012 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: chronic toxic arterial hypertension and cardiopathy are simulated by the daily introduction of a cobalt chloride solution 4 mg/kg on a metal basis once a day in stomach of experimental animals. A unit of the solution 0.2 ml is equal to cobalt 0.8 mg. The introduction is performed for 30 days.

EFFECT: method leads to developing irreversible toxic hypertension and cardiopathy that enables creating and searching the agents for preventing and treating said pathology.

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