FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to pulmonology, and can be applied for treatment and prevention of remodeling of respiratory ways and/or inflammatory lung diseases. For this purpose it is suggested to use antagonist of adenosine receptors A2B - 3- ethyl-1-propyl-8-{1 -[(3-trifluormethylphenyl)methyl] pyrasol-4-yl}-1,3,7-trihydropurin-2,6-dione.
EFFECT: invention allows to influence said conditions due to expressed inhibiting of adenosine receptors A2B, conditioning prevention and restoration of disturbed functional and morphologic properties of respiratory ways, preventing expression of some anti-inflammatory cytokines and chemokines, thus ensuring normal activity of broncho-pulmonary apparatus.
7 cl, 21 ex, 9 dwg
| Title |
Year |
Author |
Number |
| METHOD OF WOUND HEALING WITH APPLYING ANTAGONISTS OF A ADENOSINE RECEPTOR |
2005 |
- Tszen Dehvan'
- Belardinelli Luis
|
RU2385322C2 |
| METHOD OF PREVENTION AND TREATMENT OF LIVER DISEASE WITH APPLICATION OF RECEPTOR A ANTAGONISTS |
2007 |
- Tszen Dehvan'
- Chzhun Khunjan'
- Belardinelli Luis
|
RU2457842C2 |
| METHOD OF PRODUCING ANTAGONISTS OF ADENOSINE RECEPTORS A AND INTERMEDIATE PRODUCTS |
2004 |
- Ehlzein Ehlfatikh
- Kalla Rao
- Markuort Tim
- Zablotski Dzheff
- Li Sjaofehn'
|
RU2374247C2 |
| DERIVATIVES OF XANTHINE AS ANTAGONISTS OF ADENOSINE A RECEPTORS |
2003 |
- Kalla Rao
- Perri Tao
- Ehlzein Ehlfatikh
- Varkhedkar Vajbkhav
- Li Sjaofehn'
- Ibrakhim Prabkha
- Palle Venkata
- Sjao Dehnmin
- Zablotski Dzheff
|
RU2318825C2 |
| ANTAGONISTS OF ADENOSINE A RECEPTORS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR THEIR PREPARING |
2002 |
- Kalla Rao
- Perri Tao
- Ehlzein Ehlfatikh
- Varkhedkar Vajbkhav
- Li Ksiaofen
- Ibrakhim Prabkha
- Palle Venkata
- Ksiao Dengming
- Zabloski Dzheff
|
RU2318824C2 |
| PRODRUG OF ADENOSINE A RECEPTOR ANTAGONISTS |
2006 |
- Koltun Dmitrij
- Zablotski Dzheff
- Kalla Rao
|
RU2415858C2 |
| SUBSTITUTED 1,3-DIETHYL-8-VINYL-7-METHYL-3,7-DIHYDROPURINE-2,6-DIONES - ANTAGONISTS OF ADENOSINE A RECEPTOR AND USE THEREOF |
2012 |
- Ivashchenko Aleksandr Vasil'Evich
|
RU2480469C1 |
| SUBSTITUTED PHENOXYACETIC ACIDS, THEIR ESTERS AND AMIDES CONTAINING 2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PYRIN-8-YL FRAGMENTS - A ADENOSINE RECEPTOR ANTAGONISTS AND USE THEREOF |
2011 |
- Ivashchenko Aleksandr Vasil'Evich
- Mit'Kin Oleg Dmitrievich
- Kadieva Madina Georgievna
- Okun' Il'Ja Matusovich
|
RU2477726C1 |
| THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS |
2018 |
- Tanzer Eva-Maria
- Schiemann Kai
- Klein Markus
|
RU2790011C2 |
| PYRAZOLOPYRIMIDINE COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONISTS |
2019 |
- Bell, Andrew Simon
- Schreyer, Adrian Michael
- Versluys, Stephanie
|
RU2806758C2 |
