ANTIVIRAL AND ANTIMICROBIAL ORAL COMPOSITION Russian patent published in 2012 - IPC A61K38/21 A61K39/395 A61K9/14 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry and medicine. An oral composition represents a mixture consisting of a powder containing a substance comprising recombinant human interferon-α and target additives able to form a stable foam structure, specified in: polyethylene glycol, albumin, gelatine, pectin, casein, caseinate, casein hydrolysate, hydroxypropyl cellulose, polyglucin, dextrin, tragacanth, aerosil, mannitol, lactose or their mixtures, and a powder containing a substance consisting of a consortium of immunoglobulins IgA, IgG and IgM and target additives able to form a stable foam structure; it is characterised by porous structure and fragility, has a relative disintegration shrinkage at least 10 %, equivalent pore diameter 10-110 mcm at particle size no more than 100 mcm and a resting angle less than 50° and represented in the form of a solid capsule in the following proportions in 1.0 g of the composition: recombinant human interferon-α - 10000-3000000 IU, the consortium of immunoglobulins - 0.09-0.9 and target additives - the rest with the capsule coated with a layer of an enterosoluble substance.

EFFECT: invention provides the isotropic filling of the 100% preset volume of the solid capsules that exceeds the effect of a similar composition by 5% and more that ensures precise dosages of recombinant human interferon-α and the consortium of immunoglobulins.

4 cl, 4 ex