ANTIVIRAL AND ANTIMICROBIAL COMPOSITION CONTAINING CONSORTIUM OF IMMUNOGLOBULINS Russian patent published in 2012 - IPC A61K39/395 A61K9/48 

Abstract RU 2457861 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry and medicine. A composition represents a powder of a substance containing a consortium of immunoglobulins IgA, IgG and IgM and target additives able to form a stable foam structure, specified in: polyethylene glycol, albumin, gelatine, pectin, casein, caseinate, casein hydrolysate, hydroxypropyl cellulose, polyglucin, dextrin, tragacanth, aerosil, glycine, L-lysine monohydrochloride, L-arginine monohydrochloride, glucose, maltose, mannitol, lactose or their mixtures; it is characterised by porous structure and fragility, has a relative disintegration shrinkage at least 10 %, equivalent pore diameter 10-110 mcm at particle size no more than 100 mcm and a resting angle less than 50° and represented in the form of a solid capsule in the following proportions in 1.0 g of the composition: the consortium of immunoglobulins IgA, IgG and IgM 0.05-0.95 g; target additives - the rest with the capsule coated with a layer of a enterosoluble substance specified in: shellac, oleic acid, hydroxypropyl cellulose, cellulose acetate phthalate, bee wax, Tween-20, Tween-80, castor oil, polyethylene oxide or their mixture.

EFFECT: invention provides the isotropic filling of the 100% preset volume of the solid capsules that exceeds the effect of a similar composition by 5%, the maximum isotropic filling of the solid capsules ensures precise dosages of the consortium of immunoglobulins.

4 cl, 4 ex

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RU 2 457 861 C2

Authors

Chalov Viktor Vladimirovich

Aleshkin Vladimir Andrianovich

Galimzjanov Khalil Mingalievich

Afanas'Ev Stanislav Stepanovich

Rubal'Skij Oleg Vasil'Evich

Aleksanjan Igor' Jur'Evich

Gavrin Andrej Gennad'Evich

Aleshkin Andrej Vladimirovich

Galimzjanova Alija Khalilovna

Rubal'Skij Evgenij Olegovich

Afanas'Ev Maksim Stanislavovich

Afanas'Ev Denis Stanislavovich

Dates

2012-08-10Published

2008-08-05Filed