METHOD FOR STABILISING NEWCASTLE DISEASE VIRUS FOR STORAGE IN AQUEOUS SOLUTION AND METHOD FOR MAINTAINING ITS STABILITY Russian patent published in 2012 - IPC C12N7/02 

Abstract RU 2458125 C2

FIELD: medicine.

SUBSTANCE: what is described is a method for stabilising a Newcastle disease virus for storage in an aqueous solution for 6 months or more at temperature -30°C to -10°C. The method provides preparing the aqueous solution containing the Newcastle disease virus and saccharose or trehalose. The solution contains ten portions per million or less of each of reducing substances, antioxidants, sodium chloride, dextrane, mannitol, sorbitol, Tween, glutamate, polyethylene glycol, calcium chloride, phosphatidylcholine, glycine and phosphate; it has pH 7-9 and osmotic pressure 250-300 milliosmole.

EFFECT: method enables storing the virus for 6 months and more.

6 cl, 1 dwg, 9 tbl, 12 ex

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RU 2 458 125 C2

Authors

Chehn' Tser-Fyn'

Dzang Dzoukhn-Vern

Miller Dzheffri A.

Dates

2012-08-10Published

2005-11-04Filed