SET OF ARTICLES FOR FIXATION OF PROSTHESIS OR ITS PART AND/OR FILLING BONE DEFECTS AND METHOD OF FIXATION OF PROSTHESIS OR ITS PART WITH APPLICATION OF SAID SET Russian patent published in 2012 - IPC A61F2/46 A61F2/28 

FIELD: medicine.

SUBSTANCE: group of inventions relate to medicine. In accordance with first version set contains prosthesis or part of prosthesis, which have, at least, one contact surface; metal granules, which possess internal porosity; bone cement. Said granules are made on the basis of titanium. Said granules preferably possess osteoconductivity, and preferably have coating from group of osteoconductive or osteoinductive coatings, or coatings, containing bioceramics, bioglass or osteoconductive or osteoinductive molecules or liquids or cells. Titanium granules for application in said set of articles have porosity from 40 to 90% and diameter from 1 to 10 mm. Said granules preferably possess osteoconductivity. Said granules preferably have coating from group of osteoconductive or osteoinductive coatings, or coatings, containing bioceramics, bioglass or osteoconductive or osteoinductive molecules or liquids or cells. Method of fixation of prosthgesis or its part, in organism or out of organism, in bone or in artificial bone, contains the following stages: preparation of hole in bone fort reception of, at least, one contact surface of prosthesis; filling of said hole and (or) detected bone defect, at least, partially with metal granules, made on the basis of titanium, possessing internal porosity, and osteoconductivity, and preferably having coating from group of osteoconductive or osteoinductive coatings, or coatings, containing bioceramics, bioglass or osteoconductive or osteoinductive molecules or liquids or cells in such a way that, at least, part, but preferably practically entire internal wall of said hole is covered by the layer of said granules; introduction of compacting instrument into said granules into aperture in said layer and compacting said layer of granules on said internal wall in such a way that after extraction of said compacting instrument from said aperture, said aperture has shape and dimensions of, at least, one contact surface of said prosthesis; introduction of bone cement and at least one said contact surface of prosthesis into said aperture in such a way that bone cement is pressed into the layer of said granules; thus, that when said, at least, one contact surface is in required for fixation position, space between said, at least, one contact surface and internal wall is filled with said layer of granules, and bone cement is pressed into said layer. Application of titan-based metal, porous granules and bone cement in preparation of set of articles for fixation of prosthesis in bone. Application of titan-based metal, porous granules in preparation of elements for filling in bone defects. In accordance with the second version set contains porous metal granules, made on the basis of titanium, bone cement and compacting instrument for preparation of elements for filling in bone defects and (or) fixation of prosthesis or its part in bone. Set in accordance with the first or the second version, in which said compacting instrument has longitudinal direction and is provided with surface of impaction influence on longitudinal end with the aim to influence said compacting instrument in said longitudinal direction, and, at least, slightly narrowing part, preferably terminal part, narrowing in direction, opposite to said surface of impaction influence. Method of coating titanium granules, used in set of articles for fixation of prosthesis or its part and/or filling in bone defects with said titanium granules with porosity from 40 to 90% and diameter from 1 to 10 mm, which includes, at least, one of the following operations: biomimetic covering, covering in supersaturated solution; covering by plasma spraying; or electrochemical precipitation, preferably with application of salt solution bath, or electric jet spraying.

EFFECT: inventions ensure improvement of bone cement cohesion with bone and increase depth of its penetration.

35 cl, 25 dwg