FIELD: medicine, pharmaceutics.
SUBSTANCE: what is disclosed is a new aminoglycoside antibiotic which possesses excellent antibacterial activity against a bacterium inducing an infection, particularly MRSA, and also possesses low renal toxicity. A method for making said antibiotic is described. More specifically, there are disclosed a compound presented by formula (Ia) wherein the radical values are specified in the description, or its pharmaceutically acceptable salt or solvate, or mixed diastereomers of the compound; an antibacterial agent containing the compound, pharmacologically acceptable salt, solvate or mixed diastereomers; and a method for producing said compound.
EFFECT: what is disclosed is a new aminoglycoside antibiotic which possesses excellent antibacterial activity against a bacterium inducing an infection, particularly MRSA, and also possesses low renal toxicity.
23 cl, 21 ex, 1 tbl, 13 dwg
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Authors
Dates
2012-08-20—Published
2007-06-01—Filed