NEW AMINOGLYCOSIDE ANTIBIOTICS Russian patent published in 2012 - IPC C07H15/234 C07H15/22 A61K31/70 A61K31/7028 A61K31/7034 A61K31/7036 A61P31/04 

Abstract RU 2458931 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is disclosed is a new aminoglycoside antibiotic which possesses excellent antibacterial activity against a bacterium inducing an infection, particularly MRSA, and also possesses low renal toxicity. A method for making said antibiotic is described. More specifically, there are disclosed a compound presented by formula (Ia) wherein the radical values are specified in the description, or its pharmaceutically acceptable salt or solvate, or mixed diastereomers of the compound; an antibacterial agent containing the compound, pharmacologically acceptable salt, solvate or mixed diastereomers; and a method for producing said compound.

EFFECT: what is disclosed is a new aminoglycoside antibiotic which possesses excellent antibacterial activity against a bacterium inducing an infection, particularly MRSA, and also possesses low renal toxicity.

23 cl, 21 ex, 1 tbl, 13 dwg

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RU 2 458 931 C2

Authors

Kobajasi Josikhiko

Akijama Josikhisa

Murakami Takesi

Minova Nobuto

Tsusima Masaki

Khirajva Jukiko

Murakami Soiti

Abe Mitsukhiro

Sasaki Kazusige

Khosiko Sigeru

Mijake Tosiaki

Takakhasi Josiaki

Ikeda Daisiro

Dates

2012-08-20Published

2007-06-01Filed