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(19)

(11)

2 458 989

(13)

(51)

IPC

C12P21/06(2006-01-01)

C07K14/62(2006-01-01)

C07K1/12(2006-01-01)

(21) (22)

Application

2011108417/10, 2008-09-19

(24)

Start date

2008-09-19

(22)

Actual filing date

2008-09-19

(45)

Published

2012-08-20

(72)

Inventor

Jer KharishSastri Kedarnatkh NandzhundSatkh'Jaanarajana Srikantkh GollarakhosakhalliSreenivas SumaKhazra PartaShivarudrajja Mandzhunatkh Khadavanakhalli

(73)

Holder

Bajokon Limitid

METHOD FOR PRODUCING INSULIN ANALOGUES OF THEIR APPROPRIATE PRECURSORS (VERSIONS) Russian patent published in 2012 - IPC C12P21/06 C07K14/62 C07K1/12

Abstract RU 2458989 C1

FIELD: medicine.

SUBSTANCE: method for producing insulin analogues of their precursors provides a one-stage enzymatic reaction including the combinatory and concurrent use of the optimum amounts of trypsin and carboxypeptidase B which are associated and inducing a reaction in a controlled manner to avoid producing accidental undesired by-products.

EFFECT: invention allows reducing a number of operating stages and producing higher-yield and purity insulin analogues.

20 cl, 5 ex

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RU 2 458 989 C1

Authors

Jer Kharish

Sastri Kedarnatkh Nandzhund

Satkh'Jaanarajana Srikantkh Gollarakhosakhalli

Sreenivas Suma

Khazra Parta

Shivarudrajja Mandzhunatkh Khadavanakhalli

Dates

2012-08-20—Published

2008-09-19—Filed